BEST FOR

Sleep Quality, Energy, Recovery

METHOD

Small subcutaneous injection

HOW OFTEN

Once nightly, 5 days on, 2 days off.

Recommended Use

Injected once daily in the evening (since body typically makes GH at night during sleep).  5 days on, 2 days off to prevent receptors from becoming desensitized.  Typically dose Monday - Friday and taking weekends off. 

Treatment Details

Sermorelin is a synthetic peptide that stimulates the pituitary gland to naturally increase the body’s own production of growth hormone (GH). Unlike direct HGH therapy, Sermorelin encourages your body to regulate hormone levels on its own, supporting healthier, more gradual improvements in energy, sleep, metabolism, recovery, and overall vitality. It’s typically prescribed via subcutaneous injection, often taken in the evening.

Main Ingredients

Sermorelin acetate (peptide, analog of Growth Hormone–Releasing Hormone or GHRH)

Delivered in a sterile solution, sometimes with bacteriostatic water for reconstitution

Potential Side Effects

Most patients tolerate Sermorelin well, but possible side effects can include:

Redness, pain, or swelling at the injection site

Headache or flushing

Nausea or dizziness Rare: difficulty swallowing, hyperactivity, or sleep disturbances

Because it stimulates natural GH release rather than replacing it, the risk of severe side effects is generally lower than with HGH therapy

ELEVATE YOUR POTENTIAL

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high performers

For those who push their physical limits, recovery is non-negotiable. By supporting natural growth hormone (GH) production, Sermorelin promotes better sleep, faster recovery, and sustained energy.

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wellness seekers

From mood and memory to skin and sleep, Sermorelin works with your body’s own pathways to support long-term health, vitality, and healthy aging.

How Peptide
Therapy Works

Peptides are short chains of amino acids that act as messengers, helping your body function at its best.

As we age, natural peptide and growth hormone levels decline—leading to changes in energy, recovery, sleep, and metabolism.

Therapies like Sermorelin work by stimulating the pituitary gland to increase natural growth hormone production. Treatment is delivered through a small, safe injection under the skin, with dosing personalized to your body’s response—so you get targeted results without guesswork.

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TAKE OUR SHORT QUIZ

Is Peptide Therapy
Right For You?

Find out if Sermorelin is the treatment for you

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NOT SURE?

With 400+ clinics nationwide, it’s easy to talk to a Gameday specialist and find your optimal treatment

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Frequently Asked Questions

What is Sermorelin and how does it work?

Sermorelin is a peptide that stimulates your pituitary gland to naturally produce more growth hormone. By supporting your body’s own hormone pathways, it can help improve sleep, energy, recovery, metabolism, and overall vitality.

How do I know if I qualify for treatment?

Click here to begin our short pre-qualification process to see if Sermorelin is right for you. You can also talk with a Gameday medical expert for free by booking an appointment.

Who is a good candidate for Sermorelin? 

Adults experiencing low energy, poor sleep, slower recovery, or age-related declines in wellness may be a good candidate.

Will a licensed physician be guiding my treatment?

Yes. All Gameday patients work directly with licensed clinicians who design a personalized plan, monitor your progress, and adjust your treatment as needed. You’ll work with the same clinician from start to finish to ensure consistent care and the best results.

Does Gameday require insurance?

No. Gameday offers transparent, affordable pricing without the need for insurance. This means you can get evaluated and start treatment immediately—no waiting for approvals or dealing with paperwork.

What is the difference between Sermorelin and HGH?

Human Growth Hormone (HGH) therapy introduces synthetic hormones into the body. Sermorelin signals your pituitary gland to naturally produce more of its own growth hormone. This approach is considered safer, more physiologic, and often more sustainable long-term.

How is Sermorelin administered?

Sermorelin is typically given as a quick, painless injection under the skin in the lower abdomen area.

Is Sermorelin Therapy Safe?

Yes. When prescribed and monitored by a licensed medical provider, Sermorelin is safe. Most patients experience minimal side effects, with occasional mild injection site irritation or temporary fatigue.

Does Gameday Offer Telehealth?

Yes! You can now get Sermorelin in-clinic across 400+ locations or via telehealth. Whether you receive treatment in-clinic or online, the same clinician will guide your entire treatment.

A HIGHER STANDARD OF MEN’S HEALTH

The Gameday Difference

Specialized Care, Backed by Experts

With 1,200+ clinicians specialized in men’s hormone health, you’ll receive expert care you can trust. 

Fast, Free & Focused on You

Start with free consultation and complimentary labs. No hidden costs —just clear answers about your baseline and the right path forward.

400+ World-Class Clinics

Our man-cave style clinics are tailored to your comfort. Complete with on-site labs, you receive results while you wait - just 15 minutes.  

Care on Your Terms

Visit any of our 400+ nationwide clinics or connect via secure telehealth. Wherever you are, Gameday makes care seamless.